Ultrasonic Cell Disruptive

Product Description:

An ultrasonic cell disruptive equipment converts electrical energy from the ultrasonic generator into acoustic energy via a transducer. This energy effectively mixes powders with liquids, causing the liquid medium to form dense, tiny bubbles. Under high-frequency ultrasound, these bubbles rapidly implode, releasing energy akin to tiny explosions. This action forces the powder and liquid to fuse more tightly together, thereby achieving effects such as cell disruption.

Ultrasonic cell disruptive equipment is capable of disrupting tissues, bacteria, viruses, spores, and other cellular structures, as well as homogenising, emulsifying, mixing, degassing, disintegrating, dispersing, leaching, extracting, and accelerating reactions. As a result, it is widely used in laboratory research and industrial production across fields such as biology, medicine, chemistry, pharmaceuticals, cosmetics, and environmental protection.

Specification of Ultrasonic Cell Disruptive Equipment

Application

1.Cell Disruption and Biological Sample Preparation: Ultrasonic cell disruptive equipment is widely used to disrupt various cell types, including microorganisms and plant and animal cells, to obtain intracellular substances such as proteins and nucleic acids. This is of great significance for research in fields such as biology and medicine, enabling in-depth study of intracellular biological characteristics, metabolic pathways, and more.

2.Extraction of DNA, RNA and Proteins: By disrupting cell walls, ultrasonic cell disruptive equipment can rapidly and effectively release intracellular DNA, RNA and proteins, providing crucial support for subsequent molecular biology experiments and disease diagnosis.

3.Environmental Monitoring: Ultrasonic cell disruptive equipment is used to detect microbial contamination in water and soil samples. By disrupting microbial cells in water and soil, harmful substances within can be released for qualitative and quantitative analysis.

FAQ:

What types of cells can Ultrasonic cell disruptive equipment disrupt?

Our ultrasonic cell disruptor is suitable for a wide range of cell types, including:

Bacteria (e.g., E. coli)

Yeast and fungi

Plant cells (with rigid cell walls)

Animal and mammalian cells

Algae and microorganisms

Using the cavitation effect, the system effectively breaks cell membranes and walls, making it particularly efficient for both easy-to-lyse and hard-to-lyse samples.

It is widely used in molecular biology, biotechnology, and protein/DNA extraction workflows.

What is the disruption efficiency?

Our ultrasonic cell disruptor utilizes the cavitation effect to generate intense shear forces that effectively break cell membranes. Under optimized conditions, it can achieve cell disruption efficiency of over 90%, even for relatively tough samples such as yeast and certain plant cells. The actual efficiency depends on factors such as cell type, sample concentration, ultrasonic power, and processing time. With adjustable parameters (power, pulse mode, and duration), users can easily optimize conditions to achieve high yield and consistent results while preserving sensitive biomolecules like proteins and nucleic acids.

Will ultrasonic cell disruptive equipment damage proteins or DNA?

No-when properly operated, ultrasonic cell disruptive can effectively preserve proteins and DNA. The system uses the cavitation effect to break cells, but excessive heat and overexposure may affect sensitive biomolecules if not controlled. To prevent this, our equipment supports precise parameter control (power, pulse mode, and processing time) and can be used with cooling methods such as an ice bath or jacketed vessel. This ensures efficient cell disruption while maintaining the integrity and activity of proteins, DNA, and RNA. In practice, it is widely used in molecular biology and biotechnology workflows where biomolecule preservation is critical.